Actively Recruiting
Individualized Elective Neck Irradiation in NPC Patients
Led by Sun Yat-sen University · Updated on 2025-09-17
470
Participants Needed
1
Research Sites
402 weeks
Total Duration
On this page
Sponsors
S
Sun Yat-sen University
Lead Sponsor
F
First People's Hospital of Foshan
Collaborating Sponsor
AI-Summary
What this Trial Is About
To evaluate whether individualized elective neck irradiation for nasopharyngeal carcinoma based on the vertebral level of metastatic lymph nodes can reduce the incidence of radiation-related adverse effects and improve patients' quality of life，without reducing survival.
CONDITIONS
Official Title
Individualized Elective Neck Irradiation in NPC Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Newly diagnosed, untreated, non-distant metastatic, non-keratinizing nasopharyngeal carcinoma
- Nodes diagnosed with PET/CT and MRI
- Staged as T1-4N0-2 or N3 with non-bilateral lower-neck node metastasis
- Aged between 18 and 70 years
- Karnofsky performance-status score greater than 70
- Adequate blood function: leucocyte count over 4 x 10^9/L, hemoglobin over 90 g/L, thrombocyte count over 100 x 10^9/L
You will not qualify if you...
- Previous chemotherapy, surgery (except diagnostic), or radiotherapy to the neck or nasopharyngeal regions
- Previous malignancy
- Lactation or pregnancy
- Severe coexisting illness
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China, 510060
Actively Recruiting
Research Team
L
Ling-Long Tang, Prof
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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