Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06163261

Individualized Physical Activity or Patients With Non Functioning Pituitary Adenoma

Led by Vastra Gotaland Region · Updated on 2025-09-17

120

Participants Needed

1

Research Sites

200 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn about physical activity's effect on health in people who have had surgery of a non-functioning pituitary adenoma. The main questions it aims to answer are: * Do physical activity increase quality of life? * Do physical activity increase general health, cardiovascular fitness, self-efficacy and muscle strength and reduce fatigue and cardiovascular risk profile? Participants will at the start of the the study, at 6 months follow up and 12 months follow up: * Fill out health surveys * Perform a cycling test, hand strength test, chair stand test and wear and accelerometer for a week * Undergo a dual energy X-ray absorptiometry to measure muscle and fat mass * Leave blood samples Researchers will compare those who are randomized to the intervention and see a physiotherapist to get an individualized and person-centred prescription of physical activity plan and those who are randomized not to be in the intervention to see if physical activity increases quality of life and general health.¨.

CONDITIONS

Official Title

Individualized Physical Activity or Patients With Non Functioning Pituitary Adenoma

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with clinically significant non-functioning pituitary adenoma treated with surgery during the last ten years
  • Stable hormone replacement therapy for at least 6 months
  • Ability to communicate in Swedish
  • Age between 18 and 75 years
Not Eligible

You will not qualify if you...

  • Patients with any other pituitary tumors than non-functioning pituitary adenoma
  • Patients who may need tumor intervention (surgery or radiotherapy) within one year
  • Ongoing substance abuse or untreated psychiatric disorders except mild/moderate depression or anxiety treated with SSRI or SNRI
  • Use of opioids, sedatives, or hypnotics except zopiclone and zolpidem
  • History of neurological diseases with impaired mobility
  • High alcohol consumption (more than 14 units per week)
  • Ongoing cancer treatment
  • Uncontrolled hypertension or significant cardiac disease
  • Severe respiratory insufficiency
  • Severely impaired liver function (ALT or AST two times above normal)
  • Severely impaired kidney function (glomerular filtration rate below 45 ml/min)
  • Untreated hypo- or hyperthyroidism
  • Pregnancy or breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sahlgrenska Univesity Hospital

Gothenburg, Västra Götaland County, Sweden, 41345

Actively Recruiting

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Research Team

V

Victor Hantelius, Md

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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