Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT05334316

Individualizing Corticosteroid Use in Pneumonia

Led by Mayo Clinic · Updated on 2026-04-23

24

Participants Needed

1

Research Sites

107 weeks

Total Duration

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AI-Summary

What this Trial Is About

In this study, researchers propose a unique (individualized) approach to steroid treatment seeking to give the right dose of steroid to the right patient and at the right time. This study seeks to compare usual care to an individualized steroid dosing strategy by testing a marker of inflammation in the blood called C- reactive protein (CRP). The overall goal is to reduce an individual's exposure to steroids and the risk of potential side effects thereby increasing the potential benefit of using steroids to control inflammation in pneumonia.

CONDITIONS

Official Title

Individualizing Corticosteroid Use in Pneumonia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Hospitalized adult (≥ 18 years) patients
  • Community acquired pneumonia
Not Eligible

You will not qualify if you...

  • Contraindications or unwillingness to use corticosteroids by patient or provider
  • History of adrenal insufficiency, septic shock, or another absolute indication for steroid use
  • Suspected pulmonary vasculitis or other autoimmune pulmonary disorder
  • Positive pregnancy test
  • Comfort care

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

Y

Yewande Odeyemi, M.B.B.S.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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