Actively Recruiting

Age: 18Years +
FEMALE
Healthy Volunteers
NCT06039111

Indocyanine Green for Detection of Sentinel Lymph Nodes In Comparison to ICG Plus Technetium in the Evaluation of Vulvar Squamous Cell Carcinoma

Led by Hamilton Health Sciences Corporation · Updated on 2026-04-13

58

Participants Needed

1

Research Sites

165 weeks

Total Duration

On this page

Sponsors

H

Hamilton Health Sciences Corporation

Lead Sponsor

J

Juravinski Cancer Centre Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of this study is to confirm prospectively if the use of near infrared-indocyanine green (NIR-ICG) alone offers similar accuracy and sensitivity to the gold standard dual technique for sentinel lymph node detection in early stage vulvar cancer.

CONDITIONS

Official Title

Indocyanine Green for Detection of Sentinel Lymph Nodes In Comparison to ICG Plus Technetium in the Evaluation of Vulvar Squamous Cell Carcinoma

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult women aged 18 years or older
  • Diagnosed with FIGO Stage IB (> 1 mm depth of invasion) or small Stage II (4 cm) vulvar squamous cell carcinoma or cutaneous melanoma
  • Candidates for sentinel lymph node technique
  • Negative clinical groin examination and/or imaging
  • Primary unifocal vulvar tumor size less than 4 cm
Not Eligible

You will not qualify if you...

  • Prior history of pelvic, vulvovaginal, or inguinal radiation
  • Allergy or hypersensitivity to Technetium or Indocyanine Green (ICG)
  • Diagnosis of Bartholin gland cancer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hamilton Health Sciences

Hamilton, Ontario, Canada, L8V5C2

Actively Recruiting

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Research Team

A

Andra Nica, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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