Actively Recruiting

Early Phase 1
Age: 0 - 20Years
All Genders
NCT05645523

Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors

Led by St. Jude Children's Research Hospital · Updated on 2026-05-04

25

Participants Needed

3

Research Sites

162 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of the study is to find out the usefulness and safety of a dye called Indocyanine Green (ICG for short). This dye will be used to help the surgeon find lymph nodes draining solid tumors inside the abdomen that need to be removed. This may also help the surgeon to find if the cancer has moved to other lymph nodes outside of the known area. Primary Objectives * To determine the percentage of patients in whom Indocyanine Green (ICG)-guided sentinel lymph node (SLN) mapping was successful at the time of retroperitoneal lymph node dissection for staging of visceral solid tumors. * To determine the percentage of patients with grade 3 or higher adverse events related to ICG use.

CONDITIONS

Official Title

Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors

Who Can Participate

Age: 0 - 20Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient under 21 years old with visceral pediatric solid tumor suspected to be Wilms tumor or para-testicular rhabdomyosarcoma
  • Requires retroperitoneal lymph node dissection for staging
Not Eligible

You will not qualify if you...

  • History of iodide allergies
  • Unable or unwilling to provide written informed consent by patient or legal guardian
  • Pregnant female
  • Extensive prior surgery at the primary tumor or lymph node basin expected to affect lymphatic drainage

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Lurie Children's Hospital

Chicago, Illinois, United States, 60611

Actively Recruiting

2

Children's Hospital of Pittsburgh of UPMC

Pittsburgh, Pennsylvania, United States, 15224

Actively Recruiting

3

St. Jude Children's Research Hospital

Memphis, Tennessee, United States, 38105

Actively Recruiting

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Research Team

A

Andrew Davidoff, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors | DecenTrialz