Actively Recruiting

Phase Not Applicable
Age: 9Months - 60Years
All Genders
NCT04246944

Induced Membrane Properties in Children and Adults

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2025-06-08

50

Participants Needed

1

Research Sites

553 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Bone reconstruction in critical sized defect (CSD) remains a real challenge in orthopedic surgery in children and adults. The Masquelet technique is an innovative therapeutic technique, which offers a bone reconstruction in two steps, by the formation of an induced membrane (IM) around a polymethylmethacrylate (PMMA) spacer placed into the bone defect. After, PMMA removal, the cavity is filled with corticocancellous graft allowing bone healing. Up to date, all angiogenesis and osteogenic properties of IM remain unknown. The purpose of this study is to characterize angiogenesis and osteogenic properties of IM in children and adults.

CONDITIONS

Official Title

Induced Membrane Properties in Children and Adults

Who Can Participate

Age: 9Months - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients treated at CHU Amiens-Picardie for bone critical sized defect using the induced membrane reconstruction technique
  • Patients aged from 9 months to 60 years old
Not Eligible

You will not qualify if you...

  • Patients treated by another reconstruction technique for critical sized defect
  • Patients under guardianship, curators, or deprived of liberty
  • Pregnant and nursing women
  • Patients who refuse to participate or sign informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU Amiens

Amiens, France, 80054

Actively Recruiting

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Research Team

C

Céline Klein, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

0

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