Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
ID07006896

Labor Induction After Cesarean: A Randomized Trial Of Cervical Balloon With or Without Oxytocin

Led by University of Pennsylvania · Updated on 2025-07-18

100

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

A randomized trial of patients undergoing a term (≥37 weeks) induction of labor with a history of one prior Cesarean delivery, wherein the provider intends to use a Foley catheter for cervical ripening. The investigators will be comparing Foley alone with concurrent Foley and Oxytocin use at the start of the induction. With this trial, the investigators aim to test our central hypothesis that concurrent Foley and Oxytocin will decrease time to delivery without increasing risks, compared to Foley alone.

CONDITIONS

Brief Title

Induction of Labor After Cesarean Using Foley Alone vs. Concurrent Foley and Oxytocin

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Eligible for induction of labor
  • Live singleton gestation ≥37 weeks
  • History of 1 cesarean delivery
  • ≥18 years of age
  • Cephalic presentation
  • Intact membranes
  • English or Spanish speaking (Able to read/understand consent and instructions)
  • Cervical dilation <3cm and Bishop score <8
Not Eligible

You will not qualify if you...

  • >1 prior Cesarean delivery
  • Known chorioamnionitis
  • Major fetal anomaly

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19146

Actively Recruiting

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Research Team

H

Hannah Foster, MD, MAUB

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Paul A Harris, Robert Taylor, Robert Thielke...

https://pubmed.ncbi.nlm.nih.gov/18929686

Evaluating the impact of a standardized induction protocol to reduce adverse perinatal outcomes: a prospective cohort study.

Lisa D Levine, Katheryne L Downes, Rebecca F Hamm...

https://pubmed.ncbi.nlm.nih.gov/31645154

Early versus delayed amniotomy with immediate oxytocin after Foley catheter cervical ripening in multiparous women with labor induction: A randomized controlled trial.

Arifah Jamaluddin, Jerilee Mariam Khong Azhary, Jesrine Gek Shan Hong...

https://pubmed.ncbi.nlm.nih.gov/35869943

Early vs expectant artificial rupture of membranes following Foley catheter ripening: a randomized controlled trial.

Helen B Gomez Slagle, Yaneve N Fonge, Richard Caplan...

https://pubmed.ncbi.nlm.nih.gov/35135684

Balloon catheter vs oxytocin alone for induction of labor in women with one previous cesarean section and an unfavorable cervix: a multicenter, retrospective study.

Déborah Secchi, Julia Albéric, Sophie Gobillot...

https://pubmed.ncbi.nlm.nih.gov/34708257