Actively Recruiting

Age: 0 - 4Days
All Genders
Healthy Volunteers
NCT06332521

Infant Crying, a Bioacoustic Prognostic Signal for Neurodevelopment

Led by Centre Hospitalier Universitaire de Saint Etienne · Updated on 2025-05-28

1100

Participants Needed

1

Research Sites

206 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Crying is a vital communication signal for the baby. Product of a complex physiological process, it reflects not only the organization and functioning of the cortical central nervous system and the function of sympathetic and parasympathetic autonomic regulation but also the integrity of three entities: the lungs responsible for ventilatory mechanics and respiratory rhythm, the larynx and its vocal cords as a phonatory organ, and the oropharyngeal tract guaranteeing the resonance of the sound emitted by the vocal cords. Crying is usually caused by pain, discomfort, hunger, or separation from parents or other caregivers. Crying carries essential information from birth, the expression of which depends closely on the neuroanatomical and functional brain integrity of the child. On a bioacoustic level, crying consists of sequences of complex acoustic signals produced by the vocal folds and filtered by the vocal tract. The vibration frequency of the vocal cords determines the cry's fundamental frequency f0 (and the harmonic frequencies), which is responsible for its more or less low or high pitch. Other acoustic cues also characterize each baby's cry.

CONDITIONS

Official Title

Infant Crying, a Bioacoustic Prognostic Signal for Neurodevelopment

Who Can Participate

Age: 0 - 4Days
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Baby born at full term (more than 37 weeks) or prematurely (less than 37 weeks)
  • Born in the maternity ward of the Saint-Etienne University Hospital
  • Holder of parental authority who has received information about the study and their right to object
  • Holder of parental authority affiliated with or beneficiary of a social security system
  • Baby is eutrophic, with growth between the 10th and 90th percentile on neonatal curves
Not Eligible

You will not qualify if you...

  • Refusal of participation by the holder of parental authority
  • Antenatal pathology or perinatal asphyxia
  • Holder of minor parental authority
  • Holder of parental authority under curatorship or guardianship
  • Abnormal T1 audiological screening test

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chu de Saint-Etienne

Saint-Etienne, France, 42055

Actively Recruiting

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Research Team

H

HUGUES PATURAL, MD-PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Infant Crying, a Bioacoustic Prognostic Signal for Neurodevelopment | DecenTrialz