Study of Infectious Complications and Outcomes After Bladder Removal Surgery

What this Trial Is About

This research aims to better understand infectious complications in patients undergoing cystectomy, which is the surgical removal of the urinary bladder, performed for both cancerous and non-cancerous reasons. The study prospectively collects detailed medical history and clinicopathological data, focusing on markers of infection before and after surgery. It also compares patient-reported and physician-assessed complications, and explores how in-hospital complications relate to quality of life after surgery. Participants undergo cystectomy, and the study monitors inflammatory markers like interleukin-6 and procalcitonin, as well as wound drainage cultures, to evaluate early signs of infection. Researchers also compare infection rates between different types of urinary diversion surgeries, such as ileal neobladder versus ileal conduit. Follow-up periods extend up to 12 months after surgery to assess infectious complications and their impact. Participants are involved through structured follow-up interviews at 3, 6, and 12 months post-surgery, which use standardized questionnaires to record post-discharge infections and patient experiences in the hospital. The study carefully tracks in-hospital complications, antibiotic use, fever episodes, emergency visits, and hospital readmissions. Outcomes also include quality of life assessments and subjective ratings of preoperative information and complications, providing a comprehensive view of patient health and recovery over time.

Infectious Complications After Cystectomy: A Prospective Observational Study