Actively Recruiting

Age: 18Years +
All Genders
ID06911658

Infectious Complications, Associated Factors, and Prognosis After Esophagectomy for Cancer: A French, Multicenter, Retrospective Study

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-12-17

350

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to understand infectious complications after esophagectomy for cancer, focusing on patients admitted to intensive care following surgery between 2017 and 2024. These complications, such as pneumonia, are common postoperative issues that increase risks and hospital stays, significantly affecting patient quality of life. The study seeks to identify factors linked to these infections to help improve outcomes for patients undergoing this complex surgery. The study collects retrospective, pseudonymized data from multiple centers, reviewing medical records of patients who had esophagectomy for cancer and were admitted to intensive care. Data includes infection incidence, types of pathogens, resistance patterns, and antibiotic treatments used. Patient information is carefully coded and securely stored at each center, with data collection proceeding only if patients do not oppose use of their information. Participants will not be actively involved in the study process since it uses past medical records. Researchers will analyze the frequency and nature of infections within 28 days after surgery, assess related complications like sepsis or organ failure, and examine factors associated with infection occurrence. The study is observational and will monitor outcomes retrospectively to better understand infection risks and their impact on hospital stay lengths and patient prognosis.

CONDITIONS

Brief Title

Infectious Complications After Esophagectomy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients over 18 years of age
  • Underwent esophagectomy for cancer between January 1, 2017, and December 31, 2024
  • Scheduled admission to intensive care for postoperative monitoring
Not Eligible

You will not qualify if you...

  • Opposition to the use of data

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surveillance

Duration - Up to 28 days after surgery

Participants who underwent esophagectomy for cancer are observed retrospectively through their hospitalization records to assess infectious complications and related outcomes.

Data collected retrospectively from medical records

Trial Site Locations

Total: 2 locations

1

Hôpital Saint-Louis - APHP

Paris, France, 75010

Actively Recruiting

2

Saint Louis Hospital

Paris, France, 75010

Not Yet Recruiting

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Research Team

F

François DEPRET, MD-PHD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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