Ultrasound Assessment of Inferior Vena Cava Collapsibility Index to Guide Pre-operative Fluid Management in Critically Ill Pre-eclamptic Patients Compared with Standard Fluid Management

What this Trial Is About

Researchers are investigating fluid management strategies in critically ill patients with pre-eclampsia undergoing cesarean section. Pre-eclampsia is a serious pregnancy complication involving high blood pressure that can lead to severe outcomes for both mother and baby. This trial aims to compare the use of ultrasound-based measurement of the Inferior Vena Cava Collapsibility Index (IVCCI) to guide fluid therapy against the standard fluid management based on clinical evaluation in this high-risk group. In this study, participants are randomly assigned to one of two groups. The experimental group receives fluid therapy guided by IVCCI assessed using ultrasound, where fluid is administered as 300 ml of crystalloid Ringer's solution over 30 minutes and repeated if needed based on IVCCI values. The control group receives the conventional fluid regimen without additional fluids before surgery, maintaining a fixed rate of 80-100 ml/hour. The trial evaluates the safety and effectiveness of these approaches during the perioperative period. During the study, researchers monitor participants closely for post-spinal hypotension occurring within 20 minutes after spinal anesthesia and any complications arising from spinal anesthesia until delivery or within 30 minutes after spinal anesthesia, whichever occurs first. This includes using ultrasound assessments, clinical monitoring, and recording fluid responsiveness. The study ensures careful observation of maternal fluid status and blood pressure to assess outcomes, with participation spanning the preoperative and operative periods for cesarean section.

Inferior Vena Cava Collapsibility Index Guide for Preoperative Fluid Therapy in Preeclampsia