Predicting Low Blood Pressure During Hemodialysis Using Inferior Vena Cava Ultrasound Measures A Multicenter Study in Adults with End-Stage Renal Disease

What this Trial Is About

Researchers are evaluating the ability of the Inferior Vena Cava Collapsibility Index IVCCI, along with maximum and minimum diameters of the Inferior Vena Cava IVCmax and IVCmin, to predict intradialytic hypotension in adults with end-stage renal disease ESRD who are undergoing maintenance hemodialysis. This multicenter, prospective observational study aims to find a simple, non-invasive method to personalize dialysis management and reduce episodes of low blood pressure during dialysis sessions. Participants will have ultrasound measurements of IVCCI, IVCmax, and IVCmin taken once, exactly one hour after starting their dialysis session. Blood pressure will be monitored continuously during the dialysis procedure. No experimental treatments will be given, as this study observes the relationship between ultrasound measurements and blood pressure changes in patients already receiving maintenance hemodialysis. During the study, adults aged 18 to 80 with ESRD on regular hemodialysis for at least three months will be monitored at several hospitals. Researchers will assess how well the ultrasound measurements predict intradialytic hypotension by analyzing sensitivity, specificity, and optimal cutoff values. The study includes blood pressure monitoring, ultrasound scans, and collection of clinical data to improve understanding and safety of dialysis treatments over one dialysis session lasting up to four hours.

Inferior Vena Cava Collapsibility Index and Intradialytic Hypotension