Actively Recruiting
Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1
Led by Washington University School of Medicine · Updated on 2026-04-21
104
Participants Needed
1
Research Sites
376 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Adult patients with primary or secondary central nervous system malignancies will be invited to undergo a baseline \[C-11\]-CS1P1 PET scan and a follow-up scan within 24 months of the baseline scan (preferably within 6-months post-treatment).The study will describe patterns of tracer uptake in tumors and normal brain and explore how these patterns relate to MRI findings, treatments received, and clinical outcomes.
CONDITIONS
Official Title
Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female, any race
- Age 18 years or older
- Able to provide written informed consent or have a legally authorized representative to consent
- Clinical, radiographic, or pathological diagnosis of primary or secondary CNS malignancy not previously treated with radiotherapy
You will not qualify if you...
- Allergy to [C-11]-CS1P1 or its excipients
- Contraindications to PET, CT, or MRI making participation unsafe
- Prior cranial radiotherapy
- Severe claustrophobia requiring general anesthesia
- Currently pregnant or breastfeeding
- Any condition increasing risk, limiting tolerance of procedures, or interfering with data collection (e.g., advanced kidney or liver failure)
- Recent (within 12 months) participation in research involving radioactive agents exceeding regulatory radiation limits
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
T
Tammie L.S. Benzinger, M.D., Ph.D.
CONTACT
J
Jayashree Rajamanickam
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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