Actively Recruiting
Association of Preoperative Inflammatory Biomarkers With Postoperative Nausea and Vomiting in Children Undergoing Orchiopexy
Led by Diskapi Yildirim Beyazit Education and Research Hospital · Updated on 2025-09-09
170
Participants Needed
1
Research Sites
2 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how certain preoperative inflammatory biomarkers relate to the occurrence of postoperative nausea and vomiting (PONV) in children undergoing orchiopexy, a common surgery for treating cryptorchidism. This observational study focuses on children aged 1 to 8 years, exploring if markers like neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio can help predict PONV after surgery. Before surgery, blood samples will be taken to measure various inflammatory indicators such as NLR, PLR, systemic immune-inflammation index, MLR, and systemic inflammation response index. The study does not involve any experimental drugs or devices and all procedures will be part of the standard perioperative care during the elective orchiopexy. Participants will be monitored for the incidence of nausea and vomiting within six hours after surgery. Researchers will also track the need for antiemetic treatment during this period. The study aims to better understand how inflammation may contribute to PONV in pediatric patients, with the total participation covering preoperative assessment through early postoperative recovery.
CONDITIONS
Brief Title
Inflammatory Biomarkers as Predictors of PONV Following Pediatric Orchiopexy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged between 1 and 8 years
- Patients with ASA physical status I-II
- Patients scheduled for elective orchiopexy
- Obtained written informed consent from parents/guardians
You will not qualify if you...
- Patients younger than 1 year or older than 8 years
- Patients with ASA physical status III or higher
- Presence of acute infection signs
- History of previous nausea or vomiting
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Day of surgery
Participants undergo preoperative blood sample collection to measure inflammatory biomarkers related to postoperative nausea and vomiting.
1 visit (in-person)
Duration - 6 hours postoperatively
Participants are observed during the first 6 hours after surgery for nausea, vomiting, and need for antiemetic treatment.
Trial Site Locations
Total: 1 location
1
Ankara Etlik City Hospital
Altındağ, Ankara, Turkey (Türkiye)
Actively Recruiting
Research Team
E
Elif Şule Özdemir Sezgi
A
Aslı Dönmez
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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