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Study of Inflammatory Biomarkers to Predict Nausea and Vomiting After Orchiopexy Surgery in Children Aged 1 to 8 Years
Led by Diskapi Yildirim Beyazit Education and Research Hospital · Updated on 2025-09-09
170
Participants Needed
1
Research Sites
2 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating how certain preoperative inflammatory biomarkers relate to the occurrence of postoperative nausea and vomiting PONV in children undergoing orchiopexy, a common surgery for treating cryptorchidism. This observational study focuses on children aged 1 to 8 years, exploring if markers like neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio can help predict PONV after surgery. Before surgery, blood samples will be taken to measure various inflammatory indicators such as NLR, PLR, systemic immune-inflammation index, MLR, and systemic inflammation response index. The study does not involve any experimental drugs or devices and all procedures will be part of the standard perioperative care during the elective orchiopexy. Participants will be monitored for the incidence of nausea and vomiting within six hours after surgery. Researchers will also track the need for antiemetic treatment during this period. The study aims to better understand how inflammation may contribute to PONV in pediatric patients, with the total participation covering preoperative assessment through early postoperative recovery.
CONDITIONS
Brief Title
Inflammatory Biomarkers as Predictors of PONV Following Pediatric Orchiopexy
Research Team
E
Elif Şule Özdemir Sezgi
A
Aslı Dönmez
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