Actively Recruiting
Inflammatory Resolution in Cardiometabolic Health and Disease
Led by University of Aarhus · Updated on 2024-06-28
240
Participants Needed
1
Research Sites
225 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The specific aim of this study is to determine molecular pathways that differentiate metabolically healthy vs unhealthy human phenotypes, and to investigate the therapeutic potential of pro-resolving lipids. Investigators will recruit volunteers that are metabolically healthy or unhealthy that fall within three BMI ranges: lean (18.-24.9 kg/m2), overweight (25.0-29.9 kg/m2) and obese (\>30.0 kg/m2). Investigators hypothesize that metabolically healthy individuals have a superior endogenous capacity to regulate an inflammatory/resolving response.
CONDITIONS
Official Title
Inflammatory Resolution in Cardiometabolic Health and Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Informed signed consent has been obtained from the volunteer.
- The volunteer has a BMI greater than 18.5 kg/m2
- Men and women over the age of 18 are included.
You will not qualify if you...
- The study staff perceives that the individual has difficulty understanding the information.
- An MD determines that the individual is on too many medications to participate.
- The individual takes a medication but is not willing or able to wait with any potential morning medication until after their fasted blood-draw.
- The individual has increased bleeding tendency or uses anti-coagulant (blood thinning) medication.
- The individual has some form of chronic inflammation.
- The individual regularly uses medication that affects inflammatory resolution (e.g., low-dose aspirin).
- The individual uses immunosuppressive drugs (e.g., methotrexate).
- The individual regularly consumes fish oils (omega 3).
- The individual has significant gastrointestinal problems.
- The individual smokes or uses chewing tobacco.
- The individual has been drinking alcohol two days before the study visit.
- The individual has tattoos or body piercings on the forearms and/or the stomach that can affect the examination.
- The individual does not follow instructions given in the research study.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Steno Diabetes Center Aarhus, Aarhus University Hospital
Aarhus, Denmark, 8200
Actively Recruiting
Research Team
E
Emma Börgeson, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
6
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