Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT05858398

Influence of Body Composition on Chemotherapy Outcomes in Localized Breast Cancer

Led by Centre Henri Becquerel · Updated on 2026-01-02

48

Participants Needed

1

Research Sites

183 weeks

Total Duration

On this page

Sponsors

C

Centre Henri Becquerel

Lead Sponsor

E

Erasmus Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to determine if pharmacokinetics of docetaxel is modified by the body composition (assessed by the BMI but also by CT-scan) in patients treated by docetaxel as adjuvant treatment of a localized breast cancer

CONDITIONS

Official Title

Influence of Body Composition on Chemotherapy Outcomes in Localized Breast Cancer

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Woman older than 18 years
  • Diagnosis of early breast cancer
  • CT scan performed within the last 3 months including L3 vertebra level
  • Planned treatment with docetaxel at 100 mg/m² as adjuvant chemotherapy
Not Eligible

You will not qualify if you...

  • HER2 amplified or triple negative tumors
  • Pregnant or breastfeeding women
  • Patients under guardianship or curatorship
  • Receiving another cytotoxic drug or targeted therapy at the same time
  • Presence of psychosocial disorders
  • Received another cytotoxic drug or targeted therapy within 20 days before blood collection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre Henri Becquerel

Rouen, France, 76038

Actively Recruiting

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Research Team

F

Florian Clatot, Prof

CONTACT

D

Doriane Richard, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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