Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04621357

Influence of Cerebral Oedema in Intracerebral Haemorrhage

Led by University Hospital, Lille · Updated on 2026-04-22

500

Participants Needed

1

Research Sites

339 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Lille

Lead Sponsor

C

Conseil Régional Hauts-de-France, France

Collaborating Sponsor

AI-Summary

What this Trial Is About

In 2020, IntraCerebral Haemorraghe (ICH) remains the most devastating type of stroke. Besides stroke unit care, no specific treatment has been proven effective yet. Perihaematomal oedema (PHO) could be a promising therapeutic target. However, the mechanisms, the natural history as well as the clinical impact of this PHO remain unclear. The COPITCH study has been designed to answer these questions

CONDITIONS

Official Title

Influence of Cerebral Oedema in Intracerebral Haemorrhage

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have a spontaneous (non-traumatic) intracerebral haemorrhage
  • Admitted to the hospital within 12 hours of stroke onset (or last seen well for wake-up strokes)
  • Covered by French social security insurance
  • Signed the consent form
Not Eligible

You will not qualify if you...

  • Have pure intraventricular haemorrhages
  • Have secondary intracerebral haemorrhage caused by vascular malformation, venous thrombosis, head trauma, tumor, or haemorrhagic transformation of an infarct
  • Pre-admission modified Rankin score of 4 or 5
  • Life expectancy less than 1 year due to serious other medical conditions
  • Are pregnant, breastfeeding, or a woman of childbearing age without effective contraception
  • Are deprived of liberty by judicial or administrative decision
  • Are referred from other hospitals
  • Have contraindications to MRI such as claustrophobia, metallic eye foreign bodies, implanted medical devices, metal heart valves, vascular clips, or gadolinium allergy
  • Have not signed the consent form

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU de Lille

Lille, France, 59037

Actively Recruiting

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Research Team

C

Charlotte Cordonnier, MD,PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Influence of Cerebral Oedema in Intracerebral Haemorrhage | DecenTrialz