Actively Recruiting

Phase Not Applicable
Age: 0Days - 55Years
All Genders
NCT06072976

The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies

Led by Seattle Children's Hospital · Updated on 2026-04-30

116

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study explores the use of an exclusive human milk diet versus standard feeding practices to compare the influence on feeding outcomes and the gut bacteria in infants with intestinal differences.

CONDITIONS

Official Title

The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies

Who Can Participate

Age: 0Days - 55Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Infants diagnosed with gastroschisis, giant omphalocele, intestinal atresia, mid-gut volvulus, or Hirschsprung disease
Not Eligible

You will not qualify if you...

  • Infant has already started feeds
  • Infants born before 34 weeks gestation
  • Parents with contraindications to providing milk, including drug use with cocaine, fentanyl, or methamphetamine (oxycodone, suboxone, and marijuana are allowed)
  • Presence of complicated gastroschisis
  • Diagnosis of short gut syndrome
  • Additional congenital anomalies that affect milk tolerance, such as cyanotic congenital heart disease (kidney disease is allowed)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Seattle Children's Hospital

Seattle, Washington, United States, 98105

Actively Recruiting

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Research Team

L

Leonel Arellano

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies | DecenTrialz