Actively Recruiting
Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery
Led by François Lellouche · Updated on 2025-09-04
10
Participants Needed
1
Research Sites
448 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main objective is to evaluate the FreeO2 device combined with noninvasive respiratory support technique for COPD patients and postoperative bariatric surgery patients. The main hypothesis is that FreeO2 device for oxygen therapy associated with NIV or nasal high flow oxygen therapy (NHFOT) allows to reach better oxygenation and avoid hypoxemia and hyperoxia.
CONDITIONS
Official Title
Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults with respiratory acidosis (pH ≤ 7.35 and PaCO2 > 45 mmHg), with or without NIV
- Receiving oxygen therapy and/or have SpO2 below 90% on room air
- Using high flow nasal cannula at flow rates up to 30 L/min (AECOPD patients)
- Patients using CPAP before bariatric surgery due to obstructive sleep apnea
- Patients with obesity hypoventilation syndrome alongside obstructive sleep apnea (bariatric surgery patients)
You will not qualify if you...
- Younger than 18 years old
- Pregnant individuals
- Respiratory distress or conditions requiring continuous NIV or CPAP
- Glasgow coma scale below 12 or agitation/delirium/dementia limiting NIV use
- Any contraindication to NIV such as need for immediate intubation, pneumothorax, or recent esophagus surgery
- Hemodynamic instability at study start (increasing vasopressors or inotropes)
- Refusal to consent to participate in the study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Institut universitaire de Cardiologie et de Pneumologie - Université Laval
Québec, Quebec, Canada, G1V 4G5
Actively Recruiting
Research Team
F
François Lellouche, MD, PhD
CONTACT
M
Miguel Trottier, MD, CM
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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