Actively Recruiting
The Influence of Honey-flavored Yogurt on Low-grade Inflammation and Gut Health in Middle to Older Aged Women.
Led by University of California, Davis · Updated on 2026-02-10
20
Participants Needed
1
Research Sites
247 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A randomized, double-blind, crossover dietary intervention trial will test the effects of 4 weeks of daily honey-flavored yogurt intake on markers of inflammation (Th17 cytokines) and oxidative stress (NOX2, UA, RSNO) and associative changes with microbial derived metabolites (SCFAs, BAs, ellagitannins), metabolism and the fecal microbiome. The above suite of selected markers will capture diet-induced systemic changes in inflammation and oxidative stress, while assessing associated microbial changes.
CONDITIONS
Official Title
The Influence of Honey-flavored Yogurt on Low-grade Inflammation and Gut Health in Middle to Older Aged Women.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Postmenopausal female between 45 and 65 years old
- Women with no menstrual period for at least two years
- Willingness and ability to follow study protocols
- Willing to participate in all study procedures
- Body mass index (BMI) between 25.0 and 30.0 kg/m2
You will not qualify if you...
- Body mass index (BMI) of 31 kg/m2 or higher
- Having any food allergies
- Using daily anticoagulant medications including aspirin or NSAIDs
- Following vegan, vegetarian, fad, or non-traditional diets
- Using concentrated food supplements, powders, or extracts
- Consuming more than 2 cups of fruit per day
- Consuming more than 3 cups of vegetables per day
- Limiting physical activity due to chronic health conditions
- Engaging in routine high intensity exercise
- Having diabetes
- Blood pressure equal to or above 140/90 mm Hg
- Having kidney or liver disease
- Having heart disease, including past cardiovascular events or stroke
- Having abnormal metabolic or blood count lab results deemed clinically significant
- History of cancer within the past 5 years
- Having malabsorption issues
- Currently taking prescription drugs or supplements beyond general vitamins and minerals
- Unwillingness to stop supplements including herbal, plant, or fish oil a month before enrollment
- History of substance or alcohol abuse within the last 3 years
- Cannabis use
- High LDL cholesterol based on risk factors and specific thresholds
- Currently enrolled in another clinical research study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of California, Davis; Department of Nutrition
Davis, California, United States, 95616
Actively Recruiting
Research Team
R
Robert R Holt, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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