Study of Hormone Replacement Therapy and Supervised Exercise on Body Health in Postmenopausal Women Aged 45 to 65

What this Trial Is About

Researchers are evaluating the effects of supervised exercise training combined with hormonal substitution therapy on body composition, cardiovascular risk, dementia risk, osteoporosis, and insulin sensitivity in postmenopausal women. The study involves 270 postmenopausal women who experience menopausal complaints and aims to understand how these interventions influence important health factors in this population. Participants may receive hormonal substitution therapy per standard care and be randomly assigned to either an exercise group or a non-exercise group. Some women with menopausal complaints who choose not to undergo hormone therapy or supervised training can also join the study. The exercise program lasts from 12 to 24 weeks and involves supervised training sessions. Throughout the study, participants undergo evaluations at 12 and 24 weeks to monitor cardiovascular risk and insulin sensitivity. Additional assessments include measuring body composition and muscle mass. The trial monitors participants health and responses to therapy during this period to gain insight into how these interventions affect their overall well-being.

The Influence of Hormone Replacement Therapy and Supervised Exercise Training on Body Composition, Cardiovascular Risk and Insulin Sensitivity in Postmenopausal Women