Actively Recruiting

Phase Not Applicable
Age: 45Years - 65Years
FEMALE
NCT05831709

The Influence of Hormone Replacement Therapy and Supervised Exercise Training on Body Composition, Cardiovascular Risk and Insulin Sensitivity in Postmenopausal Women

Led by University Hospital, Ghent · Updated on 2025-11-18

390

Participants Needed

1

Research Sites

290 weeks

Total Duration

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AI-Summary

What this Trial Is About

This trial investigates whether supervised training in combination with hormonal substitution therapy has an impact on body composition, cardiovascular risk, risk for dementia, osteoporosis and insulin sensitivity in postmenopausal women.

CONDITIONS

Official Title

The Influence of Hormone Replacement Therapy and Supervised Exercise Training on Body Composition, Cardiovascular Risk and Insulin Sensitivity in Postmenopausal Women

Who Can Participate

Age: 45Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Postmenopausal women (diagnosed by physician) with complaints due to menopause
  • Indication for hormonal substitution therapy (except for the control group)
  • Good general health
  • BMI: 20-30 kg/m2
  • Only the use of cholesterol-, blood pressure- or/and thyroid-regulating medication is permitted
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Ghent University Hospital - Women's Clinic

Ghent, Belgium, 9000

Actively Recruiting

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Research Team

H

Herman Depypere

CONTACT

S

Study coordinator Women's Clinic

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

6

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