Study of a 12-Week Iyengar Yoga Program to Improve Biofunctional Age in Women After Menopause
Led by Insel Gruppe AG, University Hospital Bern · Updated on 2025-02-05
72
Participants Needed
1
Research Sites
39 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating whether Iyengar Yoga can have a rejuvenating effect on women after menopause by assessing their biofunctional status before and after the program. This randomized clinical trial includes postmenopausal women who experience frequent hot flushes and aims to compare the effects of a 12-week yoga intervention against no yoga practice. Participants are recruited from a university hospital and public advertisements, with careful screening for eligibility.
The study involves two groups the intervention group attends weekly 90-minute Iyengar Yoga classes led by a professional instructor and is asked to perform two additional 45-minute yoga sessions at home each week, recording these in a diary. The control group does not participate in yoga classes but undergoes the same biofunctional assessments. Both groups will have their biofunctional status measured at the start and after the 12-week period.
Participants will be assessed for their biofunctional status, including blood sample collection and evaluations related to hot flushes, inflammation markers, and oxidative balance. Researchers will monitor adherence through yoga session attendance and home practice diaries. The main outcome is the change in biofunctional age after 12 weeks. The study continues until the end of 2025, with safety and health status carefully monitored throughout.
CONDITIONS
Brief Title
Influence of Iyengar Yoga on the Bio-functional Age of Postmenopausal Women
Research Team
P
Petra o Stute, Prof. Dr. med
N
Natascha Rieben, Study Nurse
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Women after menopause defined as 12 months without periods or 6 months with high serum FSH levels or 6 weeks after surgical removal of ovaries
Age over 18 years
At least 4 hot flushes per day
No regular yoga practice in the past two years
German as native language
Willing to attend 12 yoga classes and perform two 45-minute yoga sessions at home weekly
Willing to have biofunctional status assessed and provide blood samples
Signed informed consent
You will not qualify if you...
Acute or serious illness in the past two years (e.g., cancer, major surgery)
Autoimmune or chronic inflammatory diseases (e.g., rheumatism, thyroid issues)
Mental illness such as depression or anxiety with high scores
Acute or chronic back pain or herniated disc
Compulsory participation in the trial
Attending fewer than 10 out of 12 yoga lessons
Hormone replacement therapy use
Smoking more than 20 cigarettes per day or over 20 pack-years
Consuming more than 30 grams of alcohol daily
Yoga practice in the last two years
Unable or contraindicated to participate in yoga
Incapable of judgment or under legal guardianship
Diabetes mellitus requiring special care
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Outpatient Treatment
Duration - 12 weeks
Participants assigned to the intervention group attend weekly 90-minute Iyengar Yoga classes led by a professional instructor and perform two additional 45-minute yoga sessions at home each week, documenting their practice in a diary. Participants in the control group do not receive yoga classes but undergo assessments.
Weekly visits for yoga classes (intervention group only)
Outpatient Treatment
Duration - 1 day
At the end of the 12-week period, all participants have their biofunctional status reassessed to evaluate the effects of the intervention.
1 visit (in-person)
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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Published Research Related To This Trial
G.A study protocol for a randomized controlled trial investigating the influence of Iyengar Yoga on biofunctional age and cardiovascular risk associated biomarker of postmenopausal women.