Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06377449

Influence of Ultrasound Examination of the Lungs on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients

Led by Saint Petersburg State University, Russia · Updated on 2024-12-09

186

Participants Needed

1

Research Sites

33 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the benefits of using lung ultrasound exams in the early period after heart surgery requiring cardiopulmonary bypass. The study compares the ability of ultrasound to detect early lung complications against traditional chest X-rays and CT scans. It also investigates whether early detection of lung fluid buildup affects patient outcomes in the mid-term after surgery. Participants will have lung ultrasounds on days 1, 3, 5, and 7 after surgery. In one group, medical treatments such as diuretics and anti-inflammatory drugs will be adjusted based on the ultrasound results to improve patient status. The control group will also have ultrasounds but treatment decisions will rely on standard clinical and X-ray methods without using ultrasound findings. During the hospital stay, ultrasound exams will be done every two days until discharge or death, up to 4 weeks. Researchers will measure how many patients have lung fluid at discharge, track lung complications, medication doses, and time spent at home after leaving the hospital. This follow-up aims to assess how ultrasound-guided treatment may impact recovery and outcomes after cardiac surgery.

CONDITIONS

Brief Title

Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Underwent open heart surgery with cardiopulmonary bypass between December 15, 2023, and December 15, 2024
  • Signed informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Previous open heart surgeries with cardiopulmonary bypass
  • History of lung surgery or lung cancer
  • Chronic obstructive pulmonary disease, stage III
  • Chronic kidney disease, stages 4 and 5
  • Low risk score profile by the Society of Thoracic Surgeons

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Hospital stay until discharge or death, up to 4 weeks

Participants undergo open heart surgery with cardiopulmonary bypass and begin post-operative care.

Ultrasound lung examination every second day during hospital stay

Post-operative Follow-up

Duration - Up to 4 weeks after surgery

Participants are monitored for pulmonary complications and recovery after hospital discharge.

Ultrasound lung examination every second day during hospital stay; follow-up visits depending on clinical status

Trial Site Locations

Total: 1 location

1

Saint Petersburg State University Clinic

Saint Petersburg, Sankt-Peterburg, Russia, 190020

Actively Recruiting

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Research Team

A

Aleksei A Filippov, MD, PhD

S

Sergey M Efremov, MD, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Comparative diagnostic performances of auscultation, chest radiography, and lung ultrasonography in acute respiratory distress syndrome.

Daniel Lichtenstein, Ivan Goldstein, Eric Mourgeon...

https://pubmed.ncbi.nlm.nih.gov/14695718

B-line quantification: comparing learners novice to lung ultrasound assisted by machine artificial intelligence technology to expert review.

Frances M Russell, Robert R Ehrman, Allen Barton...

https://pubmed.ncbi.nlm.nih.gov/34191132