Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT05894369

Influence Mechanism of Tumor Microenvironment Changes on Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma

Led by Renmin Hospital of Wuhan University · Updated on 2024-11-25

10

Participants Needed

1

Research Sites

138 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the predictive value and mechanism of inflammatory factors in peripheral blood on the prognosis of patients, and to explore the influencing factors of inflammation and tumor microenvironment on the efficacy of neoadjuvant chemotherapy combined with immunotherapy for esophageal cancer. To explore the predictors of neoadjuvant therapy in patients with esophageal squamous cell carcinoma.

CONDITIONS

Official Title

Influence Mechanism of Tumor Microenvironment Changes on Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 80 years
  • Definite pathological diagnosis of esophageal squamous cell carcinoma
  • Clinical stage II to IVA
  • Planned preoperative neoadjuvant chemotherapy combined with immunotherapy
  • Eastern Cooperative Oncology Group (ECOG) performance status score of 0 to 1
Not Eligible

You will not qualify if you...

  • Estimated survival time less than 6 months
  • Presence of distant metastasis at first diagnosis
  • History of malignant tumor or other malignant disease within the past 5 years
  • Pregnant women
  • Vulnerable groups including those without informed consent ability, minors, vagrants, students and subordinates of researchers, and employees of bidders

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Renmin hosptial of Wuhan University

Wuhan, Hubei, China, 430060

Actively Recruiting

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Research Team

Y

Yong Shun Chen

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Influence Mechanism of Tumor Microenvironment Changes on Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma | DecenTrialz