Utility of immediate postlobectomy fiberoptic bronchoscopy in preventing atelectasis.
A Jaworski, S K Goldberg, M D Walkenstein...
https://pubmed.ncbi.nlm.nih.gov/3289837Actively Recruiting
Led by Wielkopolskie Centrum Pulmonologii i Torakochirurgii · Updated on 2024-08-09
200
Participants Needed
1
Research Sites
4 weeks
Total Duration
Researchers are studying the effects of routine postoperative bronchoscopy on lung complications after anatomical lung resections. Respiratory complications like atelectasis and pneumonia often occur due to retained bronchial secretions that are not fully cleared by usual suctioning through an intubation tube. This trial evaluates whether using a thin flexible bronchoscope for systematic aspiration of secretions immediately after surgery can better clear the bronchial tree and reduce such complications. Participants will be randomly assigned to one of two groups: one receiving systematic bronchial aspiration using a flexible bronchoscope after surgery, and a control group receiving standard care without bronchoscopy. Surgery involves pulmonary lobectomy under general anesthesia with standard lung ventilation techniques. For the bronchoscopy group, the procedure will be done systematically to remove secretions from all main, lobar, and segmental bronchi. All patients will receive standard postoperative pain management and monitoring. During the study, participants will be closely monitored with physical exams, chest X-rays on the day of surgery and postoperative days 1 and 2, and blood tests including C-reactive protein levels. The study team will assess lung complications like atelectasis, pneumonia, and related scores within three days after surgery. Other outcomes include atrial fibrillation occurrence, surgery duration, ICU admission, and hospital stay. Safety and complications such as bleeding or infection will also be recorded. The total study duration for participants includes the immediate postoperative period up to three days after surgery.
CONDITIONS
Influence of Postoperative Bronchoscopy on Pulmonary Complications After Anatomical Lung Resections.
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo anatomical lung resection surgery under general anesthesia. At the end of surgery, suctioning of secretions from large airways is performed.
1 visit (in-person, surgery day)
Duration - Up to 3 days after surgery
Participants are randomly assigned to receive either routine postoperative care or additional systematic bronchial aspiration using flexible bronchoscopy immediately after surgery.
Daily assessments for up to 3 days
Duration - Up to 3 days after surgery
Participants are monitored for pulmonary complications including atelectasis, pneumonia, atrial fibrillation, and inflammation markers through physical exams, chest x-rays, and blood tests.
Chest x-rays on surgery day evening, postoperative days 1 and 2; daily physical exams twice a day; CRP blood test before surgery and 72 hours after surgery
Total: 1 location
1
Wielkopolskie Centrum Pulmonologii i Torakochirurgii
Poznan, Wielkopolska, Poland, 62-007
Actively Recruiting
Ł
Łukasz Gąsiorowski, MD
C
Cezary Piwkowski, Prof
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
A Jaworski, S K Goldberg, M D Walkenstein...
https://pubmed.ncbi.nlm.nih.gov/3289837I A Du Rand, P V Barber, J Goldring...
https://pubmed.ncbi.nlm.nih.gov/22003155Alan J Stolz, Jan Schutzner, Robert Lischke...
https://pubmed.ncbi.nlm.nih.gov/18958555