Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05111288

Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia

Led by Mayo Clinic · Updated on 2025-12-15

120

Participants Needed

2

Research Sites

219 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is being done to observe the effects of treatment from a device called the Bioboosti which utilizes pulsed electromagnetic waves on its ability to improve blood flow to the heart tissue in individuals with coronary artery disease (CAD).

CONDITIONS

Official Title

Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Known cardiac ischemia, non-revascularizable, or not undergoing coronary intervention during the study
  • Evidence of ischemia from clinical tests (echo, nuclear, ECG) within past 6 months
  • Left ventricular ejection fraction greater than 40% by echocardiogram within last 3 months
  • Able to complete a cardiopulmonary exercise test without major non-cardiac limitations
  • On guideline-directed optimal therapy for stable ischemia
Not Eligible

You will not qualify if you...

  • Anemia with hemoglobin less than 7 mg/dl
  • Low potassium levels below 3 mmol/L
  • Creatinine level above 5.0 mg/dl or below 0.6 mg/dl
  • Unable to exercise mainly due to orthopedic problems
  • Severe lung disease
  • Morbid obesity with BMI over 42
  • Currently pregnant
  • Breastfeeding
  • Significant arrhythmias such as ventricular tachycardia, ventricular fibrillation, frequent premature ventricular contractions, persistent atrial fibrillation, or advanced AV block
  • History of seizures
  • Unstable angina
  • Coronary spasm
  • Recent myocardial infarction within the past 90 days
  • Recent percutaneous coronary intervention within the past 90 days

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Mayo Clinic in Arizona

Scottsdale, Arizona, United States, 85259

Actively Recruiting

2

Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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