Actively Recruiting
Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK)
Led by University Hospital Heidelberg · Updated on 2026-01-28
102
Participants Needed
1
Research Sites
73 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if a longer period of lying on the back after corneal transplant surgery (Descemet Membrane Endothelial Keratoplasty, DMEK) helps the transplant stick better in the eye. It will also learn about side effects, such as back pain. The main questions it aims to answer are: * Does lying on the back for 5 days reduce the size of transplant detachment compared to lying on the back for only 1 day? * Do participants who lie on their back longer need fewer additional procedures (rebubbling)? * What symptoms or problems do participants experience with short vs. long back positioning? Researchers will compare two groups: * 1 day of back positioning * 5 days of back positioning Participants will: * Be randomly assigned to one of the two positioning groups * Wear a movement sensor that records head position * Have their eyes checked regularly with vision tests and imaging (AS-OCT) * Answer questions about their vision and comfort * Keep a diary of any positioning-related complaints, such as back pain
CONDITIONS
Official Title
Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Fuchs Endothelial Corneal Dystrophy or Bullous Keratopathy
You will not qualify if you...
- Any health conditions that prevent lying on the back (supine positioning)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Department of Ophthalmology, University Hospital Heidelberg
Heidelberg, Germany, 69120
Actively Recruiting
Research Team
M
Maximilian Friedrich, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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