Comparing Dexmedetomidine and Desflurane for Maintaining General Anesthesia in Adults Undergoing Urological Surgery

What this Trial Is About

The trial investigates the use of dexmedetomidine as an alternative to inhalational anesthetic agents for maintaining general anesthesia in patients aged 39 to 99 undergoing elective urological surgeries. It aims to address environmental concerns related to inhalational agents by evaluating dexmedetomidines potential benefits in the geriatric population. This prospective, randomized clinical study is conducted at a university hospital and includes patients scheduled for procedures such as uretero-renoscopic lithotripsy, transurethral resection of the bladder, percutaneous nephrolithotomy, and transurethral resection of the prostate. Participants are randomly assigned to receive one of two anesthesia maintenance regimens during surgery dexmedetomidine combined with remifentanil or desflurane combined with remifentanil. All patients receive a standard induction with fentanyl, propofol, and rocuronium before maintenance anesthesia is administered according to group allocation. Anesthesia depth and hemodynamic parameters are continuously monitored throughout the intraoperative period. During and after surgery, researchers collect data on anesthesia depth, hemodynamic stability, pain levels using the Visual Analog Scale, sedation using the Richmond Agitation-Sedation Scale, and recovery quality with the Modified Aldrete Score. Patients are followed postoperatively in the Post-Anesthesia Care Unit and transferred to hospital wards as appropriate. The study measures outcomes during and after surgery to evaluate anesthesia effectiveness and recovery quality, with overall participation lasting through the surgical and immediate postoperative periods.

Inhalational Agents Versus Dexmedetomidine for Maintenance of General Anesthesia