Actively Recruiting

Phase 2
Phase 3
Age: 7Years - 17Years
All Genders
Healthy Volunteers
NCT05418244

Inhaled Isopropyl Alcohol for Treatment of Nausea

Led by State University of New York at Buffalo · Updated on 2025-10-08

84

Participants Needed

1

Research Sites

218 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To determine the efficacy of inhaled isopropyl alcohol in treating nausea/vomiting among pediatric patients compared with the conventional ondansetron, or placebo treatment in a tertiary care pediatric emergency department.

CONDITIONS

Official Title

Inhaled Isopropyl Alcohol for Treatment of Nausea

Who Can Participate

Age: 7Years - 17Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a chief complaint of nausea or vomiting
  • Ages 7 to 17 years, both sexes
  • Weight greater than or equal to 15 kg
  • Baxter Animated Retching Faces (BARF) nausea severity score greater than or equal to 4 out of 10
Not Eligible

You will not qualify if you...

  • Require intravenous (IV) access
  • Inability to breathe in and out through the nose
  • Anosmia (loss of smell) reported by patient or parent
  • Allergy to isopropyl alcohol or ondansetron
  • Current or past alcohol abuse
  • Inability to communicate feeling nauseous
  • Inability to follow directions for deep nasal breathing
  • Known prolonged QT interval heart condition
  • Pregnancy
  • Received antiemetics within the last 8 hours
  • Currently taking apomorphine

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Oishei Children's Hospital

Buffalo, New York, United States, 14203

Actively Recruiting

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Research Team

H

Haiping Qiao, MBBS, MS

CONTACT

A

Alana Koehler, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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