Actively Recruiting

Age: 18Years +
FEMALE
NCT05835739

InheriteD brEast caNcer iTalian regIsTrY A Retrospective-prospective Observational Cohort Study to Evaluate Cancer Prevention Strategies in Women With a Deleterious Mutation in BRCA1-2

Led by Centro di Riferimento Oncologico - Aviano · Updated on 2023-04-28

78

Participants Needed

12

Research Sites

839 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of the study is to obtain and centralize data about cancer prevention strategies in women with a germline deleterious mutation in BRCA1-2 with or without a history of breast cancer in Italy

CONDITIONS

Official Title

InheriteD brEast caNcer iTalian regIsTrY A Retrospective-prospective Observational Cohort Study to Evaluate Cancer Prevention Strategies in Women With a Deleterious Mutation in BRCA1-2

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female sex
  • Age 18 years or older
  • Signed informed consent
  • Documented germline harmful mutation in BRCA1 and/or BRCA2
  • No history of cancer, OR radically treated breast cancer, OR stage IV breast cancer diagnosed after BRCA1-2 mutation detection
  • Admission to the participating Center since January 1, 2010 (retrospective cohort) or after site activation (prospective cohort)
Not Eligible

You will not qualify if you...

  • Other malignancies diagnosed within five years before BRCA1-2 mutation detection, except for stage I-II ovarian cancer, basal or squamous cell skin carcinoma, melanoma in situ, or cervical carcinoma in situ

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 12 locations

1

Centro di Riferimento Oncologico - Aviano

Aviano, Pordenone, Italy, 33081

Actively Recruiting

2

IRCCS AOU San Martino, IST Genova

Genova, Italy

Actively Recruiting

3

Azienda Ospedaliera Papardo

Messina, Italy

Actively Recruiting

4

ASST Ovest Milanese

Milan, Italy

Actively Recruiting

5

Azienda ospedaliera Universitaria di Modena

Modena, Italy

Actively Recruiting

6

Università degli studi di Napoli Federico II

Naples, Italy

Actively Recruiting

7

Azienda AUSL IRCCS - Reggio Emilia

Reggio Emilia, Italy

Actively Recruiting

8

ASL Roma 1, Santo Spirito

Roma, Italy

Actively Recruiting

9

IFO - Istituto Regina Elena (Oncologia medica 2)

Roma, Italy

Actively Recruiting

10

Policlinico Universitario Gemelli

Roma, Italy

Actively Recruiting

11

Città della salute Torino, PO S. Anna

Torino, Italy

Actively Recruiting

12

ASU FC Azienda Sanitaria Universitaria Friuli Centrale

Udine, Italy

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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