Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04895995

Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population

Led by Boston University Charles River Campus · Updated on 2025-03-14

95

Participants Needed

1

Research Sites

214 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The treatment of generalized anxiety disorder (GAD) in an accessible manner represents an unmet need for those with cardiovascular disease (CVD), given that patients with CVD experience numerous barriers for in-person treatment engagement. The research plan for the proposed pilot project will entail: (1) open study of the acceptability of the digital intervention (N=5), followed by (2) recruitment and randomization of 90 individuals with a history of acute CVD events and clinical levels of GAD symptoms to dCBT or a waitlist (Control) condition, using a 1.5:1 allocation (dCBT:Control).

CONDITIONS

Official Title

Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Experienced an acute cardiovascular disease (CVD) event such as myocardial infarction, stroke/transient ischemic attack, cardiac arrest, unstable angina, or congestive heart failure with hospitalization
  • Clinical levels of generalized anxiety disorder symptoms with a GAD-7 score of 10 or higher
  • Age 18 years or older
  • At least 2 months post an acute cardiac event (post-acute phase)
Not Eligible

You will not qualify if you...

  • Not English literate
  • No access to a digital device
  • Severe vision impairment
  • Severe cognitive impairment
  • Pending acute surgery or life expectancy less than 6 months
  • Self-reported schizophrenia, psychosis, bipolar disorder, seizure disorder, or current substance use disorder (except nicotine)
  • Started or changed psychotropic medication dose within the last 4 weeks
  • Received cognitive behavioral therapy for anxiety within the last 3 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Boston University

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

M

Marie Parsons, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population | DecenTrialz