Actively Recruiting
Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source
Led by CivaTech Oncology · Updated on 2025-06-17
80
Participants Needed
6
Research Sites
595 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Initial study to evaluate local control and the preferred method of attachment of the CivaSheet in the setting of suspected close or positive margins at the time of surgical tumor removal.
CONDITIONS
Official Title
Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent
- Age greater than 18 years
- Not pregnant or breastfeeding
- Able to undergo anesthesia
- Scheduled for Whipple procedure or distal pancreatectomy
- No metastatic disease
- Presence of close surgical margins
- No prior radiation therapy to the region for a separate cancer
- Confirmed borderline resectable or locally advanced pancreatic adenocarcinoma
- Received neoadjuvant chemoradiation 4 to 10 weeks before surgery
- Chemotherapy with 2 to 6 cycles of Gemcitabine + nab-paclitaxel or FOLFIRINOX
- Neoadjuvant chemoradiation administered as IMRT, 3DCRT (up to 56 Gy), or SBRT (up to 36 Gy) with pre-operative external beam dose up to 56 Gy with concurrent gemcitabine, capecitabine, or infusional 5-fluorouracil
You will not qualify if you...
- Not a surgical candidate
- Any other invasive cancer in the past 5 years except basal or squamous cell skin cancer
- Candidate for percutaneous irreversible electroporation (IRE)
- Recurrent or previously resected tumors
- Documented history of alcoholism or drug abuse
- Participation in other clinical trials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Tampa General Hospital
Tampa, Florida, United States, 33612
Not Yet Recruiting
2
Rush University Cancer Center
Chicago, Illinois, United States, 60612
Completed
3
Advocate Christ Medical Center
Oak Lawn, Illinois, United States, 60453
Actively Recruiting
4
University Medical Center LSU
New Orleans, Louisiana, United States, 70112
Completed
5
Fox Chase Cancer Center
Philadelphia, Pennsylvania, United States, 19111
Completed
6
Virginia Commonwealth University Massey Cancer Center
Richmond, Virginia, United States, 23298
Completed
Research Team
C
Carra Castagnero
CONTACT
K
Kristy Perez, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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