Actively Recruiting
Led by Ottawa Heart Institute Research Corporation · Updated on 2026-05-06
1208
Participants Needed
4
Research Sites
25 weeks
Total Duration
O
Ottawa Heart Institute Research Corporation
Lead Sponsor
C
Canadian Institutes of Health Research (CIHR)
Collaborating Sponsor
Researchers are evaluating an intervention aimed at increasing long-term smoking abstinence among tobacco smokers who visit emergency departments and other busy hospital and community healthcare settings. This randomized controlled trial focuses on improving quit rates by combining behavioral incentives with tailored follow-up support. Smoking causes many preventable health problems, including heart disease, stroke, lung diseases, and cancers, and quitting can reduce these risks. The study addresses the gap in quit smoking support offered in high-volume care environments in Canada. The intervention group receives a "Quit Card," which is a $300 gift card to purchase nicotine replacement therapies at pharmacies, along with self-help materials and six months of personalized telephone counseling from a Nicotine Addiction Treatment Specialist. Participants are randomly assigned to either this Quit Card Intervention (QCI) group or a usual care group that receives no intervention. The study design allows for direct comparison of the impact of this behavioral and drug-related support against standard care. Participants will be followed for up to 12 months, with assessments at 4, 26 (6 months), and 52 weeks after enrollment. Researchers will measure smoking abstinence, quit attempts, smoking reduction, use of cessation medications or e-cigarettes, behavioral support use, quality of life, healthcare visits, hospital admissions, deaths, and cost-effectiveness. Follow-up includes telephone assessments and linkage to health administrative data. The total participation duration covers one year with multiple evaluations to understand long-term outcomes and healthcare impacts.
CONDITIONS
The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments
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You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) at emergency department
Duration - 6 months
Participants receive a Quit Card gift card, self-help information, and tailored smoking cessation counseling with telephone follow-up support for six months.
Telephone follow-up visits over 6 months
Duration - 6 months
Participants are followed for an additional 6 months to assess smoking abstinence and other outcomes.
Follow-up assessments at 4, 26, and 52 weeks after enrollment
Total: 4 locations
1
Civic Hospital
Ottawa, Ontario, Canada
Actively Recruiting
2
General Hospital
Ottawa, Ontario, Canada
Actively Recruiting
3
Riverside Hospital
Ottawa, Ontario, Canada
Actively Recruiting
4
University of Ottawa Heart Institute
Ottawa, Ontario, Canada
Actively Recruiting
C
Chantelle Masterson, BPhil
E
Evyanne Wooding, R.Kin
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Kerri A Mullen, Aditi Garg, Frederick Gagnon...
https://pubmed.ncbi.nlm.nih.gov/34688291