Actively Recruiting

Phase Not Applicable
Age: 8Years - 18Years
All Genders
NCT07426315

Innovative Methodologies for Neuroplasticity in Developmental Age With the Use of Virtual Reality

Led by IRCCS Centro Neurolesi Bonino Pulejo · Updated on 2026-02-23

108

Participants Needed

1

Research Sites

154 weeks

Total Duration

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AI-Summary

What this Trial Is About

Neurodevelopmental disorders, such as Cerebral Palsy (CP), Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), are complex conditions that affect various aspects of children's development. Despite advancements in treatments, conventional rehabilitative interventions tend to focus on specific aspects, often overlooking the holistic needs of the patient. Many of these interventions fail to engage children, who may feel uninvolved or demotivated. Innovative technologies, such as immersive virtual reality (IVR), offer a promising alternative to make rehabilitation more engaging and comprehensive. This study aims to evaluate the effects of IVR-based rehabilitation on children and adolescents with neurodevelopmental disorders, focusing on improvements in cognitive, motor, and social functions. We hypothesize that IVR will enhance social interaction, attention, motor skills, and overall quality of life. The study will include children and adolescents aged 8 to 18 years, diagnosed with ADHD, ASD, and cerebral palsy. The CAR-EN platform, which provides a highly customizable therapeutic environment, will be used. Assessments will measure cognitive, motor, and social skills before and after the intervention. We expect immersive virtual reality to lead to significant improvements in the participants' cognitive, motor, and social abilities. These findings could potentially contribute to a shift in therapeutic guidelines, offering more effective treatments for children with neurodevelopmental disorders.

CONDITIONS

Official Title

Innovative Methodologies for Neuroplasticity in Developmental Age With the Use of Virtual Reality

Who Can Participate

Age: 8Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children and adolescents aged 8 to 18 years
  • Diagnosed with Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), or Cerebral Palsy (CP)
  • Ability to understand and follow instructions for the intervention
  • Adequate cognitive, motor, and social skills to participate in the rehabilitation program
  • Informed consent obtained from a parent or legal guardian
Not Eligible

You will not qualify if you...

  • Younger than 8 years or older than 18 years
  • Severe cognitive impairments or intellectual disabilities preventing participation
  • Diagnosed with major psychiatric disorders such as severe depression or schizophrenia
  • Diagnosed with neurological disorders not included in the study, such as epilepsy
  • Severe motor impairments that prevent interaction with the virtual reality platform
  • Uncontrolled medical conditions like severe cardiovascular, respiratory, or endocrine diseases
  • Lack of informed consent from a parent or legal guardian
  • Participation in another intervention or study that may interfere with this rehabilitation program
  • Behavioral issues or extreme anxiety that prevent following instructions or using the virtual reality system

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

IRCCS Neurolesi Bonino Pulejo

Messina, Messina, Italy, 98124

Actively Recruiting

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Research Team

F

Francesca Cucinotta

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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