Actively Recruiting
Innovative Treatment of Chemotherapy-Induced Painful Peripheral Neuropathy in Adolescents and Young Adults With Cancer: A Two Arm Pilot Study
Led by M.D. Anderson Cancer Center · Updated on 2025-11-06
38
Participants Needed
1
Research Sites
211 weeks
Total Duration
On this page
Sponsors
M
M.D. Anderson Cancer Center
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
To evaluate the efficacy and safety of Scrambler therapy (ST) for chemotherapy-induced painful peripheral neuropathy (CIPN), and the impact of ST on physical functioning and quality of life (QoL) in adolescents and young adults (AYA) cancer patients. In this proposed study, we will conduct a two-arm prospective, randomized wait-list controlled clinical trial to investigate the effectiveness of ST on pain and CIPN in AYAs with cancer.
CONDITIONS
Official Title
Innovative Treatment of Chemotherapy-Induced Painful Peripheral Neuropathy in Adolescents and Young Adults With Cancer: A Two Arm Pilot Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Both genders aged 15-39 years
- Patients with chemotherapy-induced painful peripheral neuropathy (CIPN) with at least moderate symptoms of pain (4 or higher on a 0-10 scale) or neuropathy
- Patients who have had cancer and are not currently receiving active treatment
- Patients who speak English and can complete questionnaires alone or with help
- Written informed consent obtained from adults or parents/guardians for adolescents, with assent from adolescents aged 15-17 years
You will not qualify if you...
- Inability to walk or stand without assistance or ambulatory devices
- Bone or central nervous system metastases affecting walking, balance, or gait
- History of other known or unknown causes of acute or chronic neuropathic or non-neuropathic pain
- Presence of implanted intrathecal drug-delivery system, spinal cord or peripheral nerve stimulator, or certain metal implants such as pacemakers or defibrillators
- History of epilepsy
- Skin damage where electrodes would be placed
- Prior scrambler therapy treatment
- Use of pain medications for reasons other than CIPN
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
M D Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
S
Salahadin Abdi, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
2
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