Actively Recruiting
Inside a Neuron - Ex Vivo Evaluation of Cerebral and Cerebellar Neuronal Activity.
Led by Fondazione IRCCS Policlinico San Matteo di Pavia · Updated on 2025-03-26
60
Participants Needed
1
Research Sites
154 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Understanding the functioning of human neurons has always been a key element, especially with regard to the translation of the inputs they receive into actions that determine human behavior. However, the vast majority of studies have been performed in animal models due to the difficulty in maintaining neuronal functions ex vivo. Recently, techniques have been illustrated that allow us to obtain slices of brain tissue removed during neurosurgical interventions. The patch-clamp and HD-MEA (high density - microelectrodes array) techniques, used until now for animal samples, can allow us to study the functioning of the neural cells that make up these slices. Furthermore, the exploration of the functioning of the aforementioned cells in pathological conditions can open the field for further therapeutic perspectives.
CONDITIONS
Official Title
Inside a Neuron - Ex Vivo Evaluation of Cerebral and Cerebellar Neuronal Activity.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with a brain or cerebellum primary or secondary tumor scheduled for partial or complete surgical removal.
You will not qualify if you...
- Patients with a brain or cerebellum primary or secondary tumor scheduled only for a biopsy procedure.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Pavia, Italy, 27100
Actively Recruiting
Research Team
F
Francesco Guerrini, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here