Actively Recruiting
Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients with Brain Lesions.
Led by Erasme University Hospital · Updated on 2025-02-19
40
Participants Needed
1
Research Sites
97 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Neurovascular uncoupling (NVU) represents a major source of potential bias for the identification of eloquent brain regions through activation procedures in blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI). Same region shows proper pattern in glucose metabolism in victiny of brain lesions, investigated with positron emitted tomography with radiolabeled glucose (PET-FDG) This research project aims at investigating the mechanisms of NVU by using a multimodal noninvasive imaging approach in neurosurgical patients.
CONDITIONS
Official Title
Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients with Brain Lesions.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients must have prior imaging showing a potentially resectable intra-cerebral mass lesion
- Patient must be included before surgery, chemotherapy, and radiation
You will not qualify if you...
- Previous brain surgery
- Respiratory failure
- Asthma
- Claustrophobia
- Previous adverse reaction to gadovist (contrast agent)
- Pregnancy and breastfeeding
- Diabetes (type I and II)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
HUB-Erasme Hospital
Brussels, Belgium, 1060
Actively Recruiting
Research Team
T
Thibault Vanbutsele
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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