Study of Insomnias Effects on DNA Stability, Heart and Metabolic Health, and Lifestyle in Adults and Older Adults

What this Trial Is About

Insomnia is a common sleep disorder affecting many adults worldwide, including athletes, older adults, university students, and people with metabolic syndrome. It is linked to various health problems such as metabolic dysfunction, cardiovascular diseases, and damage to DNA. This study aims to understand how insomnia impacts body composition, fitness, metabolism, and DNA stability across these groups, while identifying biological and lifestyle factors that contribute to its effects. The research seeks to provide insights that could help develop prevention and treatment strategies for insomnia-related health issues. Participants will undergo various assessments including cardiopulmonary exercise testing, bioelectrical impedance analysis for body composition, and micronucleus assay to examine DNA damage. Physical activity, sleep quality, and lifestyle behaviors will be evaluated through questionnaires and wearable devices. Blood samples will measure glucose, lipids, insulin, and hormone levels. These evaluations will take place during a single visit, with some participants wearing monitoring devices to track sleep and activity patterns. During the study, researchers will measure insomnia severity, daytime sleepiness, sleep quality, body composition, DNA integrity, cardiorespiratory fitness, metabolic flexibility, and insulin resistance. Additional assessments include nutrition, physical activity, stress, depression, substance use, and screen time. The study involves healthy young adults, athletes, older adults, university students, and individuals with metabolic syndrome, with participation lasting for a single visit. The data gathered will help understand insomnias impact on health and guide future clinical interventions.

Insomnia´s Impact on DNA Stability, Cardio-metabolic Health and Lifestyle Behaviors