Actively Recruiting
Inspiratory Muscle Training in Amiotrophyc Lateral Sclerosis
Led by University Ramon Llull · Updated on 2026-02-17
44
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Amyotrophic Lateral Sclerosis (ALS) progressively damages the nerve cells responsible for voluntary muscle movement. Over time, this leads to weakness in different muscles such as those used for movement or breathing. Breathing problems are one of the main causes of complications and reduced survival in people with ALS. This happens because the inspiratory muscles-those that help draw air into the lungs-gradually lose strength. The study has the aim to explore the benefits of training inspiratory muscles in ALS patients in order to maintain the setrength of these muscles for as long as possible and look the impact on respiratory function.
CONDITIONS
Official Title
Inspiratory Muscle Training in Amiotrophyc Lateral Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with spinal ALS
- Men and women
- Diagnosis date less than two years ago, according to the El Escorial criteria
- Maximal inspiratory pressure (MIP) above the lower limit of normal
- Preserved lung function (FVC 280%, FEV1 280%, FEV1/FVC 280%) with normal values in supine position
You will not qualify if you...
- Signs of respiratory muscle weakness (MIP and MEP below lower limit of normal and abnormal decubitus tests)
- Nocturnal hypoventilation
- Inability to perform measurement tests
- Inability to understand and perform the exercises
- Any contraindication to the use of inspiratory muscle training
- Severe psychiatric illness
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
ADELA Gipuzkoa
Donostia / San Sebastian, Gipuzka, Spain, 20015
Actively Recruiting
Research Team
J
Jordi Vilaró, Professor
CONTACT
N
Nora Saez, Research coordinator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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