Actively Recruiting

Age: 40Years - 75Years
All Genders
NCT06440018

INSPIRE: a Multi-Cancer Early Detection Study

Led by Singlera Genomics Inc. · Updated on 2025-02-21

5350

Participants Needed

1

Research Sites

31 weeks

Total Duration

On this page

Sponsors

S

Singlera Genomics Inc.

Lead Sponsor

F

Fudan University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research constitutes a multi-centric, case-control designed investigation aimed at developing and implementing a blinded validation of a machine learning-powered, multi-cancer early detection model. This is to be achieved through the prospective collection of blood specimens from newly diagnosed cancer patients and individuals devoid of a confirmed cancer diagnosis

CONDITIONS

Official Title

INSPIRE: a Multi-Cancer Early Detection Study

Who Can Participate

Age: 40Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 40 and 75 years
  • Clinically and/or pathologically diagnosed cancer (for case participants)
  • No prior or ongoing systemic or local cancer treatments such as surgery, radiochemotherapy, endocrinotherapy, targeted therapy, immunotherapy, or interventional therapy (for case participants)
  • Able to provide written informed consent and willing to follow all study procedures
  • Without confirmed cancer diagnosis (for control participants)
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding women
  • Known prior or current diagnosis of other types of malignancies (for case participants)
  • Participation in an interventional clinical trial within the past 30 days with experimental drug use (for case participants)
  • History of organ, bone marrow, or stem cell transplant
  • Blood transfusion within 30 days before screening
  • Received therapy in the past 14 days before screening, including oral or IV antibiotics, glucocorticoids, azacitidine, decitabine, procainamide, hydrazine, or arsenic trioxide
  • Failure to collect blood samples on schedule or samples not meeting requirements
  • No previous history of malignancy (for control participants)
  • Unsuitable for the trial as determined by researchers (for control participants)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fudan University

Shanghai, Shnaghai, China, 200433

Actively Recruiting

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Research Team

Z

Zhixi Su, PHD

CONTACT

R

Rui Liu

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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INSPIRE: a Multi-Cancer Early Detection Study | DecenTrialz