Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
Healthy Volunteers
NCT06496425

Inspiring Seniors Towards Exercise Promotion to Protect Cognition

Led by Emory University · Updated on 2026-04-30

80

Participants Needed

2

Research Sites

124 weeks

Total Duration

On this page

Sponsors

E

Emory University

Lead Sponsor

A

Alzheimer's Association

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to test the benefits of beat-accented music stimulation (BMS) for behavioral changes of physical activity (PA) in older adults with subjective memory complaints. Specific Aims are to determine (1) whether BMS beneficially influences PA behaviors and psychological responses to PA in older adults for 6 months, and (2) whether exercising with BMS differently influences physical and cognitive functioning as well as quality of life in older adults. To test the effects of BMS on PA, participants will be randomly assigned to an exercise intervention that either includes BMS or does not include BMS. Participants will attend a supervised group strength training (ST) (30 minutes per day) and aerobic exercise (AE) (30-50 minutes per day) session for 3 days per week for the first 2 months, 1 day per week for the next 2 months (while encouraging participants to independently perform both AE and ST on other days), and independently for the final 2 months (always with a goal of performing \>150minutes per week AE and 3 days per week of ST for 30 minutes per day).

CONDITIONS

Official Title

Inspiring Seniors Towards Exercise Promotion to Protect Cognition

Who Can Participate

Age: 65Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults at least 65 years old.
  • Ambulatory and able to walk without pain or assisted walking devices.
  • Able to speak and read English.
  • Healthy enough to exercise at moderate intensity, with or without medical clearance.
  • Living in the community for the study duration.
  • Having reliable transportation.
  • Having a safe space at home or nearby for unsupervised exercise (at least 6 feet by 6 feet).
  • Being low-active, less than 60 minutes per week of moderate aerobic exercise and no strength training in the past 3 months.
  • Having subjective cognitive complaints defined by a Cognitive Change Index score of 15 or higher.
Not Eligible

You will not qualify if you...

  • Diagnosis of neurological disorders such as dementia, Parkinson's disease, multiple sclerosis, or stroke.
  • Known exercise contraindications including uncontrolled hypertension, joint problems, diabetes, or metabolic conditions.
  • Current cancer treatment.
  • Stroke or neural impairment within the past 6 months.
  • Hip, knee, or spinal fracture or surgery within the past 6 months.
  • Unable or unwilling to attend intervention classes.
  • Currently participating in other physical activity or fitness research.
  • Use of medication for cognitive impairment.
  • Regularly drinking more than 14 alcoholic beverages per week or current illicit drug use.
  • Meeting thresholds for cognitive impairment or clinical depression.
  • Uncorrected hearing or visual impairments.
  • Unable to understand study procedures.
  • Having a household member already participating in this study.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Emory University

Atlanta, Georgia, United States, 30324

Actively Recruiting

2

UNC Greensboro

Greensboro, North Carolina, United States, 27412

Completed

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Research Team

S

Study Team

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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