Actively Recruiting
Insulin and Insulin Pulses During Fasting
Led by Mayo Clinic · Updated on 2025-10-01
60
Participants Needed
1
Research Sites
154 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Fasting hyperglycemia contributes disproportionately to nonenzymatic glycosylation and the microvascular complications of type 2 diabetes. However, little is known about the regulation of glucose concentrations in the fasting state relative to what is known about the postprandial state. The proposed experiment is part of a series of experiments designed to establish how glucagon and insulin interact with their receptors to control fasting glucose in health and in prediabetes.
CONDITIONS
Official Title
Insulin and Insulin Pulses During Fasting
Who Can Participate
Eligibility Criteria
You may qualify if you...
- People with normal or impaired fasting glucose and normal or impaired glucose tolerance
You will not qualify if you...
- HbA1c greater than 6.5%
- Body mass index (BMI) of 35 Kg/m2 or higher
- Use of any glucose-lowering medications including metformin or sulfonylureas
- Positive pregnancy test for female subjects at enrollment or during the study
- History of upper abdominal surgery such as adjustable gastric banding, pyloroplasty, or vagotomy
- Active systemic illness or cancer
- Symptomatic macrovascular or microvascular disease
- Hematocrit less than 35%
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
K
Kim Osmundson, CCRP
CONTACT
J
Jeanette Laugen
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here