Actively Recruiting
Intake of Nitrate-rich Vegetables and Their Effect on Inflammatory Molecules and Oral Microbiota of Patients With Periodontitis
Led by University of Guadalajara · Updated on 2024-08-16
60
Participants Needed
1
Research Sites
236 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Vegetables, mainly green leafy ones and some others like beets, are a rich source of nitrate. Nitrate metabolism has shown benefits to the body and there are recent studies that agree that the consumption of nitrates from vegetables can modify the oral microbiota by increasing species with nitrate-reducing capacity, which are also bacteria that are associated with oral health.
CONDITIONS
Official Title
Intake of Nitrate-rich Vegetables and Their Effect on Inflammatory Molecules and Oral Microbiota of Patients With Periodontitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and/or women from 30 to 65 years old
- Voluntary participation and signing the written informed consent
- Not receiving nutritional treatment at the time of uptake
- Availability to attend all scheduled visits
- Have an indication to receive nonsurgical periodontal treatment (NSPT)
- Interdental clinical insertion loss 653mm and 655mm in the buccal or oral area of two or more non-adjacent teeth
- Detectable depths 65 5mm in two or more teeth
- Radiographic evidence of periodontal bone loss
You will not qualify if you...
- Trauma-Induced Gingival Recessions
- Cervical caries
- History of bleeding diathesis
- Pregnant or nursing women
- BMI <18.5 kg / m2
- History of any of the following self-reported diseases: type 2 diabetes mellitus, high blood pressure, kidney or liver disease, inflammatory bowel diseases, autoimmune diseases and/or use of medications to control these diseases
- Having or presenting a high risk of infection by tuberculosis, hepatitis B or Human Immunodeficiency Virus (HIV)
- Use of antibiotics (including antibiotic oral rinse) 6 months prior to or during the study
- Having received specialized periodontal treatment in the previous 6 months
- Smoking habit
- Require an interpreter or not understand Spanish to attend or provide written material
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Integral Dental Clinics CUCS UDG
Guadalajara, Jalisco, Mexico, 44340
Actively Recruiting
Research Team
L
Lucrecia Carrera, PhD
CONTACT
N
Nydia S Sanchez, Bachelor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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