Actively Recruiting
High Frequency Ventilation with Echocardiography and Chest Ultrasound to Help Lung Recruitment in Preterm Infants
Led by Alexandria University · Updated on 2025-05-28
72
Participants Needed
2
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying the use of high frequency oscillatory ventilation HFOV to help open the lungs in preterm newborns born between 32 and 37 weeks gestational age who have moderate to severe breathing difficulties. The study also aims to compare chest ultrasound with routine chest X-rays to monitor lung opening and to assess heart function using functional echocardiography. This research is focused on improving care for these vulnerable infants by evaluating these monitoring methods and ventilation support. The study involves preterm infants who require invasive breathing support through HFOV within the first 24 hours of life. Researchers will use chest ultrasound and echocardiography to monitor lung recruitment and heart blood flow during this treatment. The main study period covers the first three days after birth when these assessments will be performed to evaluate lung and heart function. Participants will undergo chest ultrasound exams and heart flow measurements during the initial three days of life. The study will measure lung recruitment using ultrasound, blood flow through the superior vena cava, and estimated pulmonary artery pressure. These assessments will help researchers understand the effects of HFOV on lung opening and heart function in preterm babies. The total participation time is around three days with ongoing monitoring during this period.
CONDITIONS
Brief Title
Integrated Echocardiography and Chest Ultrasound Assessment of Lung Recruitment in Preterm Infants
Research Team
M
Marwa M Farag, PhD
M
Mohamed Hany Saad, MBBCh
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