Actively Recruiting

Phase Not Applicable
Age: 1Hour - 3Days
All Genders
NCT05726578

Integrated Echocardiography and Chest Ultrasound Assessment of Lung Recruitment in Preterm Infants

Led by Alexandria University · Updated on 2025-05-28

72

Participants Needed

2

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary aim of this work is to evaluate the role of high frequency oscillatory ventilation (HFOV) in recruitment of lung in preterm newborns 32 to 37 weeks gestational age with moderate to severe respiratory distress. The secondary aim is to evaluate the role of chest ultrasound in monitoring of lung recruitment in comparison to routine chest x ray in those babies. Also cardiac hemodynamics will be assesed using functional echocardiography.

CONDITIONS

Official Title

Integrated Echocardiography and Chest Ultrasound Assessment of Lung Recruitment in Preterm Infants

Who Can Participate

Age: 1Hour - 3Days
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Infants 32 to 37 weeks gestational age
  • Respiratory distress within the first 24 hours of life
  • Intubated and receiving invasive respiratory support using high frequency oscillatory ventilation (HFOV)
  • Signs of respiratory distress including rapid breathing (respiratory rate > 60/min), grunting, nasal flaring, chest retractions, or need for oxygen or respiratory support
Not Eligible

You will not qualify if you...

  • Known major congenital anomalies including congenital heart diseases
  • Fetal hydrops
  • Babies with congenital heart diseases

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Marwa Mohamed Farag

Alexandria, Egypt, 0325

Actively Recruiting

2

Neonatal Intensive Care Unit (NICU) of Alexandria University Maternity Hospital.

Alexandria, Egypt, 21131

Not Yet Recruiting

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Research Team

M

Marwa M Farag, PhD

CONTACT

M

Mohamed Hany Saad, MBBCh

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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