Actively Recruiting
Integrated Multi-omics Data for Personalized Treatment of Obesity-associated Fatty Liver Disease
Led by Institut Investigacio Sanitaria Pere Virgili · Updated on 2024-11-13
1104
Participants Needed
1
Research Sites
1070 weeks
Total Duration
On this page
Sponsors
I
Institut Investigacio Sanitaria Pere Virgili
Lead Sponsor
H
Hospital Universitari Sant Joan
Collaborating Sponsor
AI-Summary
What this Trial Is About
The investigators seek to analyze the samples provided by patients with obesity-associated fatty liver disease at the multi-omics level and to integrate the results with clinical information, genotypic variants, and factors influencing inter-organ crosstalk. The main aim is to improve the interpretation of fatty liver disease associated with obesity and diabetes by developing predictive models built with algorithms from artificial intelligence. The challenge is to decipher the flow of information by exploring contributing factors, proximate causes of regulatory defects, and maladaptive responses that may promote therapeutic approaches.
CONDITIONS
Official Title
Integrated Multi-omics Data for Personalized Treatment of Obesity-associated Fatty Liver Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Body mass index greater or equal to 40 kg/m^2.
- Body mass index between 35 and 40 kg/m^2 with high-risk comorbidities (diagnosis or treatment for hypertension, dyslipidemia, or type 2 diabetes mellitus).
- Positive psychiatric evaluation.
- Age greater or equal to 18 years old.
You will not qualify if you...
- Legal or illegal drug consumption, including alcohol.
- Diagnosis of Hepatitis.
- Current cancer diagnosis or treatment.
- Clinical or analytical evidence of severe illness.
- Clinical or analytical evidence of chronic or acute inflammation.
- Clinical or analytical evidence of infectious diseases.
- Clinical or analytical evidence of terminal illness.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hospital Universitari Sant Joan
Reus, Tarragona, Spain, 43204
Actively Recruiting
Research Team
J
Jorge Joven, Professor
CONTACT
H
Helena Castañé, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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