Actively Recruiting
Integrated PTSD and Chronic Pain Treatment
Led by Weill Medical College of Cornell University · Updated on 2025-12-17
20
Participants Needed
1
Research Sites
85 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Posttraumatic stress disorder (PTSD) occurs in approximately 7% of adults in the general population. PTSD greatly impacts quality of life and often co-occurs with other conditions such as chronic pain. Individuals with co-morbid PTSD and chronic pain demonstrate higher PTSD symptoms and pain (as well as greater anxiety, depression, disability, and opioid use) compared to those with only one of those conditions. Gold standard treatments exist for both PTSD (e.g., Prolonged Exposure; PE) and chronic pain (e.g., Cognitive Behavioral Therapy for Chronic Pain; CBT-CP) and are generally offered sequentially (i.e., one at a time for the condition that is most prominent). Treating these conditions separately may overlook their interconnected nature, which may reduce efficacy and increase dropout. Thus, there is a need for an intervention to target both simultaneously, which may be more effective and efficient than treating conditions sequentially. This is a single-arm pilot study to assess the feasibility and acceptability of an integrated treatment for adults with comorbid PTSD and chronic pain. The intervention consists of 12 90-minute virtual psychotherapy sessions scheduled twice per week. The treatment draws from modules in PE and CBT-CP including psychoeducation, exposure to feared/avoided situations and activities, processing of exposures, behavioral activation, breathing and relaxation techniques, sleep hygiene, symptom monitoring, and structured homework assignments. Baseline and post-treatment assessments will be conducted.
CONDITIONS
Official Title
Integrated PTSD and Chronic Pain Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older
- English-speaking
- Current diagnosis of PTSD confirmed by CAPS-5 (any trauma type)
- Chronic pain with pain severity of 4 or higher on a 0-10 scale over the past 3 months
- Medically stable for outpatient therapy attendance
- Stable on psychotropic medication for at least 60 days
- Agree not to change medication or pain treatments during the study unless medically necessary
You will not qualify if you...
- Lifetime diagnosis of schizophrenia, other psychotic disorder, or bipolar I disorder
- Participation in evidence-based psychological treatment for PTSD or chronic pain in the past 3 months
- Participation in such treatments during the study is not allowed
- Moderate or severe substance use in the past 90 days
- Cognitive impairment preventing informed consent or completing assessments
- Current homicidal or suicidal risk as judged by the principal investigator
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Weill Cornell Medicine
New York, New York, United States, 10065
Actively Recruiting
Research Team
M
Mariel Emrich, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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