Using Bioelectrical Impedance Analysis and Kidney Function Tests to Improve Nutritional Assessment in Adults on Hemodialysis
Led by University of Tartu · Updated on 2025-03-13
30
Participants Needed
1
Research Sites
8 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying how combining body composition measurements from Bioelectrical Impedance Analysis BIA with estimates of kidney function eGFR can improve health assessments for people undergoing hemodialysis. Many patients on dialysis face challenges like malnutrition, muscle loss, and fluid imbalances, but current methods rely on basic tests and observations. This study aims to provide a more accurate, non-invasive way to monitor nutrition and overall health in these patients.
The study will analyze how BIA parameters such as fat mass, fat-free mass, total body water, and phase angle relate to eGFR in hemodialysis patients. It will explore whether using these measures together offers a better understanding of nutritional status and kidney function. The research will also evaluate the prevalence of malnutrition and protein-energy wasting among patients receiving chronic hemodialysis.
Participants will undergo body composition assessments using BIA and have their kidney function monitored through eGFR readings over a three-month period. Researchers will collect clinical data related to dialysis needs and nutritional health. The main outcome measured is the correlation between body composition and kidney function, alongside evaluations of malnutrition and phase angle, to help improve patient monitoring and treatment decisions.
CONDITIONS
Brief Title
Integrating BIA and eGFR for Nutritional Status in Hemodialysis Patients
Research Team
A
Anum Basit Masters student, BSc
A
Alastair Forbes, MD
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Receiving hemodialysis treatment for at least 6 months
You will not qualify if you...
Pregnant or breastfeeding
Presence of major second pathology
Having a pacemaker implanted
Recent major surgery
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Monitoring
Duration - 3 months
Participants undergoing hemodialysis are observed to assess nutritional status using bioelectrical impedance analysis and estimated glomerular filtration rate measurements.
Periodic assessments during hemodialysis sessions over 3 months
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Published Research Related To This Trial
Body Composition Changes Following Dialysis Initiation and Cardiovascular and Mortality Outcomes in CRIC (Chronic Renal Insufficiency Cohort): A Bioimpedance Analysis Substudy.