Actively Recruiting

All Genders
ID04249375

Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System

Led by University of British Columbia ยท Updated on 2026-05-01

150

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of British Columbia

Lead Sponsor

G

Genome British Columbia

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research focuses on addressing adverse drug reactions in children taking three common types of medications: antibiotics, pain relievers, and mental health drugs. The study aims to test a pharmacogenomic panel that helps predict how these medications might affect individual patients. Researchers will also explore how doctors, pharmacists, patients, and families understand and use these test results. The study involves implementing a pilot program for pharmacogenomic testing to improve medication safety and effectiveness. Data collection forms will be created to gather information from prescribing physicians. Pharmacogenomic reports will be developed to share test results with healthcare providers, patients, and their families. The study will assess the perceptions and use of these tests and reports by all involved parties. Participants will be monitored to provide pharmacogenomic recommendations about the risk of gene-related adverse events before or during treatment with analgesics, antibiotics, or mental health medications. A total of 150 participants will be involved. The study will collect information on how the test results influence medication decisions and safety. Participation may last as long as needed to gather this information, with ongoing communication and data collection from healthcare providers and families.

CONDITIONS

Brief Title

Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants will be enrolled if they can benefit from pharmacogenomic testing. This means their physician is considering the use of a drug that is part of the panels (analgesics, antibiotics, and mental health medication) or they are already using one.
Not Eligible

You will not qualify if you...

  • Patients who do not speak or understand English.

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Monitoring

Duration - Up to 8 years

Participants are observed to understand how pharmacogenomic testing results are perceived and utilized by physicians, pharmacists, patients, and their families.

Participants have pharmacogenomic recommendations provided prior to or during treatment with analgesics, anti-infectives, or psychotropics.

Trial Site Locations

Total: 2 locations

1

Children's and Women's Health Centre of British Columbia

Vancouver, British Columbia, Canada, V6H 3V4

Actively Recruiting

2

Children's Hospital of Eastern Ontario

Ottawa, Ontario, Canada, K1H 8L1

Actively Recruiting

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Research Team

B

Bruce Carleton, PharmD.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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