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Study on Combining Smoking Cessation Methods and Low-Dose CT Screening to Detect Lung Cancer in Smokers Aged 50 to 74
Led by Oulu University Hospital · Updated on 2026-02-06
1200
Participants Needed
5
Research Sites
504 weeks
Total Duration
AI-Summary
What this Trial Is About
This research aims to evaluate the effectiveness of different methods to help people stop smoking combined with low-dose CT LDCT screening for lung cancer. It focuses on individuals aged 50 to 74 who have a significant smoking history and are current smokers. The study compares smoking cessation methods, the impact of LDCT screening on lung cancer detection, the stage at which lung cancer is found, and survival specific to lung cancer. Participants are randomly assigned to one of three groups smoking cessation using a smartphone application plus LDCT screening, smoking cessation using written materials plus LDCT screening, or smoking cessation with the smartphone application alone without LDCT screening. The interventions involve digital support for quitting smoking and lung cancer screening using low-dose CT scans. The study tracks outcomes over time, including smoking cessation rates and lung cancer findings. During the study, researchers will monitor smoking cessation success at three, 12, and 24 months, verify smoking status with carbon monoxide measurements, and assess lung cancer incidence and screening results at various time points including up to ten years. Participants will be asked to use the assigned smoking cessation method and, if applicable, undergo LDCT scans. The study lasts several years to capture both short- and long-term outcomes related to smoking behavior and lung cancer detection.
CONDITIONS
Brief Title
Integrating Smoking Cessation With Low-dose CT-screening for Lung Cancer
Research Team
J
Jussi P Koivunen, MD, PhD
S
Sanna Iivanainen, MD, PhD
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