Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06702891

Integrative Analysis of Exosome-Mediated Single-Cell Transcriptomics and Proteomics in Gastric Cardia Cancer

Led by Qilu Hospital of Shandong University · Updated on 2025-02-07

20

Participants Needed

1

Research Sites

145 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is an observational study with a case control design. This study included patients with gastric cancer confirmed by pathological diagnosis of gastric tissue, and matched the control population according to age, gender, etc. In this study, researchers collected clinical information and multiple biological samples such as serum and tissue tissue from the study subjects. The researchers combined exosome sequencing, proteomics and single-cell RNA sequencing to explore the heterogeneity of cardia cancer, identify specific biomarkers and potential therapeutic targets for cardia cancer, and provide a basis for the development of new diagnostic tools and therapeutic strategies.

CONDITIONS

Official Title

Integrative Analysis of Exosome-Mediated Single-Cell Transcriptomics and Proteomics in Gastric Cardia Cancer

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed informed consent form
  • Age 18 years or older
  • Confirmed gastric cancer diagnosis by pathological examination, including high-level intraepithelial neoplasia, early gastric cancer, or advanced gastric cancer
Not Eligible

You will not qualify if you...

  • Gastrointestinal surgery within the past 1 year
  • Previous neoadjuvant chemotherapy with residual tumor after partial gastrectomy
  • Daily use of proton pump inhibitors, antibiotics, probiotics, prebiotics within the past month or recent hormone therapy
  • Infectious diseases or other digestive system diseases interfering with results, such as inflammatory bowel disease or irritable bowel syndrome

AI-Screening

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Trial Site Locations

Total: 1 location

1

Qilu Hospital of Shandong University

Jinan, Shandong, China, 250012

Actively Recruiting

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Research Team

X

Xiaoya Wang, Bachelor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Integrative Analysis of Exosome-Mediated Single-Cell Transcriptomics and Proteomics in Gastric Cardia Cancer | DecenTrialz